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Abstract Text: The COVID-19 pandemic has rapidly spread across the world, bringing death, illness, disruption to daily life, and economic crisis to businesses and individuals. The situation has been exacerbated after the schools and companies reopened due to economic pressure. One of the key failures in COVID-19 containment is underlined by the inability of our…

Abstract Text: The SARS-CoV-2 coronavirus, the cause of the COVID-19 global pandemic, is efficiently spread and has reached over 27 million confirmed cases as of September 8, 2020. There is therefore an urgent need for new technologies that can provide early detection of virus, reducing the transmission and infection rate. The goal of this proposal…

Abstract Text: Available tools for detection of SARS-CoV-2 virus require extensive sample preparation and/or expensive lab- based equipment to obtain accurate results. The objective in this proposal is to build a touch-screen sensor array to directly capture, detect, and identify model SARS-CoV-2 virus particles with minimal false alarms. This ambi- tious goal will be achieved…

Abstract Text: The ultimate goal of this proposal is to develop a novel platform technology for automatic surveillance and tracing of airborne SARS-CoV-2 virus particles in real time. The centerpiece of this proposal is the “Rolosense” technology which leverages a DNA micromotor as the virus sensing and transduction material (VSTM) that can be detected by…

Abstract Text: Coronavirus 2019 (COVID-19) has afflicted 6.2 million Americans and killed 190,000 as of early September 2020 (WHO website); a roughly 3% mortality. Between a shortage in testing and unidentified asymptomatic individuals, the actual number of those infected could be 6 to 24-fold higher than that reported. SARS-CoV-2 (CoV-2), the virus underlying the disease,…

Abstract Text: The devastation caused by emerging pathogens with fast transmission capacity, such as SARS-CoV-2, has demonstrated the importance of preparedness for future viral outbreaks; this includes the ability for fast deployment of in-situ testing tools and epidemiological surveillance with high temporal and spatial resolution; particularly in places that are most vulnerable to becoming reservoirs…